Research for infection protection
  • germs
  • Adenovirus
  • Aspergillus niger
  • Bovine virus diarrhea
  • Clostridium difficile
  • Candida albicans
  • Candida albicans
  • Coronavirus
  • Corynebacterium
  • Escherichia coli
  • Helicobacter pylori

Author: Stauffer F et al. (2013) Source: American Journal of Infection Control 41 (2013): 1007-11.


Stauffer F et al. (2013)

Acceptability and tolerability of liquid versus gel and standard versus virucidal alcohol-based hand rub formulations among dental students.

Background: Hand disinfection is capable of preventing the spread of microorganisms in the clinical setting. However, the willingness to disinfect hands often is unsatisfactory even though hand disinfectants are easily accessible. It is probable that hand disinfection formulations based on alcohol have an influence on the compliance rate. Hence, the present study analysed the acceptance and skin tolerability of four different alcohol-based gel or liquid products possessing bactericidal activity or additional virucidal activity.

Methods: The prospective longitudinal study was conducted with students of the Bernhard Gottlieb University Clinic of Dentistry in Vienna. The test persons were randomly distributed to dental treatment cabins, equipped with the following alcohol-based products: a liquid bactericidal preparation (A, alsoft E); a virucidal liquid preparation (B, Manorapid Synergy); a virucidal ethanol-based hand gel (C, Spirigel complete); and an ethanol-based hand gel with bactericidal activity (D, Sterillium Gel). The subjects applied the products every day for one week, and then assessed the subjective acceptance (e.g. colour, fragrance) and the products’ skin tolerability in a WHO questionnaire with a seven-step Likert scale.

Results: Based on the evaluation of 82 questionnaires, all four products can be considered “good”. The assessment of the liquid products (A and B) did not reveal significant differences. For the subjective acceptance of the hand gels, product D (Sterillium Gel) achieved significantly higher values than preparation C. The test persons evaluated the user-friendly application and the smell as better. The skin tolerability of the two hand gels was observed to be significantly different as well. For all tested criteria (e.g. appearance of the skin, intactness, skin moisture level), Sterillium Gel obtained better ratings.

Conclusions: The acceptance of alcohol-based hand disinfectants among healthcare personnel is the prerequisite for high compliance rates with hand hygiene. The study shows that the user acceptance does not depend on general categories (bactericidal/virucidal or liquid/gel product), but rather on a preparation’s individual formulation.

American Journal of Infection Control 41 (2013): 1007-11.