Research for infection protection
  • germs
  • Adenovirus
  • Aspergillus niger
  • Bovine virus diarrhea
  • Clostridium difficile
  • Candida albicans
  • Candida albicans
  • Coronavirus
  • Corynebacterium
  • Escherichia coli
  • Helicobacter pylori

Author: Mattner F et al. Source: Dtsch Arztebl Int 2012; 109(3): 39-45.

Mattner F et al.

Current recommendations on preventing the spread of multidrug-resistant Gram-negative pathogens in Germany.

The number of infections due to Gram-negative pathogens is on the rise worldwide. In Germany, the most common pathogens causing nosocomial infections in intensive care units are bacteria such as Pseudomonas aeruginosa, Klebsiella spp., Escherichia coli, and Enterobacter spp. Infections with these multidrug-resistant organisms are hard to treat and involve high morbidity and mortality. 

Within the scope of an expert workshop, the Permanent Committee on General and Hospital Hygiene and the Special Committee on Infection Prevention and Antibiotic Resistance in Hospitals of the German Society for Hygiene and Microbiology (DGHM) reviewed existing data on the epidemiology and diagnostic evaluation of multidrug-resistant Gram-negative pathogens, and carried out selective review of the relevant literature, with special attention to national guidelines. Based on the results, the experts formulated recommendations.

The suggested hygiene measures for managing colonised and infected patients in non-outbreak situations depend on the clinical environment’s risk profile. In addition, the expert panel presents a definition of multidrug-resistant Gram-negative organisms.

However, the authors emphasise that the recommendations are mostly to be considered “expert opinion,” rather than “evidence-based.”

Dtsch Arztebl Int 2012; 109(3): 39-45.

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