Research for infection protection

Multi-resistant bacteria

Bacteria that acquired resistant to different antibiotics. These bacteria pose major therapeutic problems, for example methicillin-resistant Staphylococcus aureus strains (MRSA) or multidrug-resistant Gram-negative pathogens (MRGN).

Generally, disinfectants are also active against multi-resistant bacterial strains as they have a totally different mode of action than antibiotics. The active substances in disinfectants attack large parts of the bacterial cell (e.g. proteins, membranes) using unspecific mechanisms for effect, while antibiotics usually only influence one specific step of the metabolism (e.g. inhibition of cell wall synthesis). Bacteria can relatively easily overcome the latter by developing resistances, but not the unspecific chemical attack of disinfectants.